EGI releases beta version of new Geodesic Transcranial Electrical Neuromodulation (GTEN) 100 Research System
27 June 2016 – EGI is pleased to announce the release of the beta version of our new GTEN 100 Research System, which brings an entirely new level of precision and rigor to non-invasive neuromodulation. This research system builds on EGI’s new generation of source imaging software, GeoSource 3.0 Research, which includes the ability to build highly detailed and realistic head models using an individual’s MRI scan and unique brain conductivity pattern.
Non-invasive, transcranial electrical neuromodulation (tDCS/tACS) is a promising method for modulating brain function. It is actively used in research to evaluate its efficacy for treatment of a number of neurological disorders where pharmaceutical intervention is ineffective and to study fundamental brain processes such as brain plasticity. Potential interest to researchers include major areas of unmet medical need, such as depression, schizophrenia, epilepsy, tinnitus, chronic pain, migraine, and rehabilitation following trauma or stroke. The GTEN 100 system is also being used in research and clinical trials using other forms of non-invasive neuromodulation, such as Transcranial Magnetic Stimulation (TMS), and invasive neuromodulation, such as deep brain stimulation (DBS).
The GTEN 100 Research product offers the ability to employ high-resolution electrical head models to predict current flow and estimate current density at the cortical surface. Using sophisticated planning software, information derived from the electrical head models can be used to formulate stimulation plans that are informed by advanced functional imaging, such as dEEG and realistic anatomical constraints, rather than based on best guesses. Additionally, because the GTEN 100 system is built on EGI’s dense array EEG platform, the brain response to stimulation can be recorded in order to understand the neuromodulatory effects and to monitor for unintended stimulation effects.
Coupled with EGI’s new GeoSource 3.0 Research source estimation platform, functionally significant cortical regions can be identified and be used as targets for neuromodulation. Using EGI’s proprietary whole head, dense array Geodesic Sensor Net technology, the GTEN 100 system will allow maximal flexibility in choosing any of 256 EEG electrodes for transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), or pulsed direct current stimulation (tPCS).The use of the Geodesic Sensor Net electrode placement system and integration with EGI’s sensor digitization technology helps to ensure reproducibility from session to session.
The culmination of 25 years of interdisciplinary research, the GTEN 100 neuromodulation system integrates EGI’s core technologies and expands the capabilities of EGI’s research products from brain monitoring and dESI to research into therapeutic intervention. The GTEN 100 Research beta package is sold as an upgrade to the GES 400 EEG platform with one of three levels of the GeoSource 3.0 electrical source imaging package. The GTEN 100 Research Neuromodulation System is sold for research use only at this time pending the results of clinical trials currently underway.