Epilepsy Research

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Barzegaran, E., Joudaki, A., Jalili, M., Rossetti, A. O., Frackowiak, R. S., & Knyazeva, M. G. (2012). Properties of functional brain networks correlate with frequency of psychogenic non-epileptic seizures. Front Hum Neurosci, 6, 335. doi:10.3389/fnhum.2012.00335

 

Birca, A., Lassonde, M., Lippé, S., Lortie, A., Vannasing, P., & Carmant, L. (2015). Enhanced EEG connectivity in children with febrile seizures. Epilepsy Research, 110(0), 32-38. doi:http://dx.doi.org/10.1016/j.eplepsyres.2014.11.008

 

Birot, G., Spinelli, L., Vulliemoz, S., Megevand, P., Brunet, D., Seeck, M., & Michel, C. M. (2014). Head model and electrical source imaging: A study of 38 epileptic patients. Neuroimage Clin, 5, 77-83. doi:10.1016/j.nicl.2014.06.005

 

Boly, M., & Maganti, R. (2014). Monitoring epilepsy in the intensive care unit: Current state of facts and potential interest of high density EEG. Brain Injury, 28(9), 1151-1155. doi:10.3109/02699052.2014.920525

 

Bosl, W. J. (2016). Informatics for EEG biomarker discovery in clinical neuroscience. (PhD), Boston University.  

 

Brodbeck, V., Lascano, A. M., Spinelli, L., Seeck, M., & Michel, C. M. (2009). Accuracy of EEG source imaging of epileptic spikes in patients with large brain lesions. Clinical Neurophysiology, 120(4), 679-685. doi:10.1016/j.clinph.2009.01.011

 

Brodbeck, V., Spinelli, L., Lascano, A. M., Pollo, C., Schaller, K., Vargas, M.-I., . . . Seeck, M. (2010). Electrical source imaging for presurgical focus localization in epilepsy patients with normal MRI. Epilepsia, 51(4), 583-591. doi:10.1111/j.1528-1167.2010.02521

 

Brodbeck, V., Spinelli, L., Lascano, A. M., Wissmeier, M., Vargas, M.-I., Vulliemoz, S., . . . Seeck, M. (2011). Electroencephalographic source imaging: a prospective study of 152 operated epileptic patients. Brain, 134(10), 2887-2897. doi:10.1093/brain/awr243

 

Brodbeck, V., Thut, G., Spinelli, L., Romei, V., Tyrand, R., Michel, C. M., & Seeck, M. (2010). Effects of repetitive Transcranial Magnetic Stimulation on spike pattern and topography in patients with focal epilepsy. Brain Topography, 22, 267-280. doi:10.1007/s10548-009-0125-2

 

Carey, H. J., Manic, M., & Arsenovic, P. (2016). Epileptic Spike Detection with EEG using artificial Neural Networks. Paper presented at the 2016 9th International Conference on Human System Interactions (HSI).

 

Carey III, H. J. (2016). EEG Interictal Spike Detection Using Artificial Neural Networks. (MS Thesis), Virginia Commonwealth University.  

 

Coito, A., Michel, C. M., van Mierlo, P., Vulliémoz, S., & Plomp, G. (2016). Directed functional brain connectivity based on EEG source imaging: methodology and application to temporal lobe epilepsy. IEEE Transactions on Biomedical Engineering, 63(12), 2619-2628.

 

Custo, A., Vulliemoz, S., Grouiller, F., Van De Ville, D., & Michel, C. (2014). EEG source imaging of brain states using spatiotemporal regression. NeuroImage, 96, 106-116. doi:10.1016/j.neuroimage.2014.04.002

 

Datta, A., Oser, N., Bechtel, N., & Weber, P. (2011). Epilepsy and Cognition in Childhood. Epileptologie, 28, 98-106.

 

Datta, A. N., Oser, N., Ramelli, G. P., Gobbin, N. Z., Lantz, G., Penner, I. K., & Weber, P. (2013). BECTS evolving to Landau-Kleffner Syndrome and back by subsequent recovery: a longitudinal language reorganization case study using fMRI, source EEG, and neuropsychological testing. Epilepsy Behav, 27(1), 107-114. doi:10.1016/j.yebeh.2012.12.025

 

Del Felice, A., Arcaro, C., Storti, S. F., Fiaschi, A., & Manganotti, P. (2013). Slow spindles' cortical generators overlap with the epileptogenic zone in temporal epileptic patients: an electrical source imaging study. Clin Neurophysiol, 124(12), 2336-2344. doi:10.1016/j.clinph.2013.06.002

 

Del Felice, A., Broggio, E., Valbusa, V., Gambina, G., Arcaro, C., & Manganotti, P. (2014). Transient epileptic amnesia mistaken for mild cognitive impairment? A high-density EEG study. Epilepsy & Behavior, 36(0), 41-46. doi:http://dx.doi.org/10.1016/j.yebeh.2014.04.014

 

Del Felice, A., Foroni, R., Manganotti, P., Storti, S. F., Ricciardi, G. K., Bashat, D. B., . . . Nicolato, A. (2014). The use of electrical source imaging in targeting lesional mesial temporal epilepsy for radiosurgical treatment. Epileptic Disorders, 16(4), 528-532. doi:10.1684/epd.2014.0697

 

Del Felice, A., Magalini, A., & Masiero, S. (2015). Slow-oscillatory Transcranial Direct Current Stimulation Modulates Memory in Temporal Lobe Epilepsy by Altering Sleep Spindle Generators: A Possible Rehabilitation Tool. Brain Stimulation. doi:10.1016/j.neuroscience.2010.01.019

 

Del Felice, A., Storti, S. F., & Manganotti, P. (2014). Sleep affects cortical source modularity in temporal lobe epilepsy: A high-density EEG study. Clinical Neurophysiology(0). doi:http://dx.doi.org/10.1016/j.clinph.2014.12.003

 

Duffy, F. H., Eksioglu, Y. Z., Rotenberg, A., Madsen, J. R., Shankardass, A., & Als, H. (2013). The frequency modulated auditory evoked response (FMAER), a technical advance for study of childhood language disorders: cortical source localization and selected case studies. BMC Neurol, 13, 12. doi:10.1186/1471-2377-13-12

 

Feng, R., Hu, J., Pan, L., Wu, J., Lang, L., Jiang, S., . . . Zhou, L. (2016). Application of 256-channel dense array electroencephalographic source imaging in presurgical workup of temporal lobe epilepsy. Clinical Neurophysiology, 127(1), 108-116. doi:10.1016/j.clinph.2015.03.009

 

Frohlich, J., Senturk, D., Saravanapandian, V., Golshani, P., Reiter, L. T., Sankar, R., . . . Jeste, S. S. (2016). A Quantitative Electrophysiological Biomarker of Duplication 15q11.2-q13.1 Syndrome. PLoS One, 11(12), e0167179. doi:10.1371/journal.pone.0167179

 

Grabowski, T. J. (2016). A Novel Mutual-Information-Guided Sparse Feature Selection Approach for Epilepsy Diagnosis Using Interictal EEG Signals. Paper presented at the Brain Informatics and Health: International Conference, BIH 2016, Omaha, NE, USA, October 13-16, 2016 Proceedings.

 

Groening, K., Brodbeck, V., Moeller, F., Wolff, S., van Baalen, A., Michel, C. M., . . . Siniatchkin, M. (2009). Combination of EEG-fMRI and EEG source analysis improves interpretation of spike-associated activation networks in paediatric pharmacoresistant focal epilepsies. NeuroImage, 46(3), 827-833. doi:10.1016/j.neuroimage.2009.02.026

 

Grouiller, F., Delattre, B. M., Pittau, F., Heinzer, S., Lazeyras, F., Spinelli, L., . . . Vargas, M. I. (2015). All-in-one interictal presurgical imaging in patients with epilepsy: single-session EEG/PET/(f) MRI. European Journal of Nuclear Medicine and Molecular Imaging, 42(7), 1133-1143.

 

Grouiller, F., Jorge, J., Pittau, F., van der Zwaag, W., Iannotti, G. R., Michel, C. M., . . . Lazeyras, F. (2016). Presurgical brain mapping in epilepsy using simultaneous EEG and functional MRI at ultra-high field: feasibility and first results. Magnetic Resonance Materials in Physics, Biology and Medicine, 1-12.

 

Grouiller, F., Thornton, R. C., Groening, K., Spinelli, L., Duncan, J. S., Schaller, K., . . . Vulliemoz, S. (2011). With or without spikes: localization of focal epileptic activity by simultaneous electroencephalography and functional magnetic resonance imaging. Brain, 134(Pt 10), 2867-2886. doi:10.1093/brain/awr156

 

Guo, J. N., Kim, R., Chen, Y., Negishi, M., Jhun, S., Weiss, S., . . . Feeney, E. (2016). Impaired consciousness in patients with absence seizures investigated by functional MRI, EEG, and behavioural measures: a cross-sectional study. The Lancet Neurology, 15(13), 1336-1345.

 

Hassan, M., Merlet, I., Mheich, A., Kabbara, A., Biraben, A., Nica, A., & Wendling, F. (2016). Identification of interictal epileptic networks from dense-EEG. Brain Topography, 1-17.

 

Holmes, M. D. (2008). Dense array EEG: Methodology and new hypothesis on epilepsy syndromes. Epilepsia, 49(s3), 3-14. doi:10.1111/j.1528-1167.2008.01505.x

 

Holmes, M. D. (2011). Dense Array EEG & Epilepsy. Management of Epilepsy – Research, Results and Treatment(Chpt. 8), 153-168.

 

Holmes, M. D., Brown, M., & Tucker, D. M. (2004). Are “generalized” seizures truly generalized? Evidence of localized mesial frontal and frontopolar discharges in absence. Epilepsia, 45(12), 1568-1579. doi:10.1111/j.0013-9580.2004.23204.x

 

Holmes, M. D., Quiring, J. M., & Tucker, D. M. (2010). Evidence that juvenile myoclonic epilepsy is a disorder of frontotemporal corticothalamic networks. NeuroImage, 49(1), 80-93. doi:10.1016/j.neuroimage.2009.08.004

 

Holmes, M. D., Tucker, D. M., Quiring, J. M., Hakimian, S., Miller, J. W., & Ojemann, J. G. (2010). Comparing Noninvasive Dense Array and Intracranial Electroencephalography for Localization of Seizures. Neurosurgery, 66(2), 354-362. doi:10.1227/01.NEU.0000363721.06177.07

 

Hyde, D. E., Duffy, F. H., & Warfield, S. K. (2012). Anisotropic partial volume CSF modeling for EEG source localization. NeuroImage, 62(3), 2161-2170. doi:10.1016/j.neuroimage.2012.05.055

 

Iannotti, G. R., Grouiller, F., Centeno, M., Carmichael, D. W., Abela, E., Wiest, R., . . . Pittau, F. (2016). Epileptic networks are strongly connected with and without the effects of interictal discharges. Epilepsia, 57(7), 1086-1096.

 

Kargiotis, O., Lascano, A. M., Garibotto, V., Spinelli, L., Genetti, M., Wissmeyer, M., . . . Vulliemoz, S. (2014). Localization of the epileptogenic tuber with electric source imaging in patients with tuberous sclerosis. Epilepsy Res, 108(2), 267-279. doi:10.1016/j.eplepsyres.2013.11.003

 

Klamer, S., Rona, S., Elshahabi, A., Lerche, H., Braun, C., Honegger, J., . . . Focke, N. K. (2015). Multimodal effective connectivity analysis reveals seizure focus and propagation in musicogenic epilepsy. NeuroImage, 113, 70-77.

 

Lantz, G., Grave de Peralta, R., Spinelli, L., Seeck, M., & Michel, C. M. (2003). Epileptic source localization with high density EEG: how many electrodes are needed? Clinical Neurophysiology, 114(1), 63-69.

 

Lantz, G., Grouiller, F., Spinelli, L., Seeck, M., & Vulliemoz, S. (2011). Localisation of Focal Epileptic Activity in Children Using High Density EEG Source Imaging. Epileptologie, 28, 84-90.

 

Lantz, G., Spinelli, L., Seeck, M., Menendez, R. G. d. P., Sottas, C. C., & Michel, C. M. (2003). Propagation of interictal epileptiform activity can lead to erroneous source localizations: a 128-channel EEG mapping study. Journal of Clinical Neurophysiology, 20(5), 311-319.

 

Lascano, A. M., Perneger, T., Vulliemoz, S., Spinelli, L., Garibotto, V., Korff, C. M., . . . Seeck, M. (2016). Yield of MRI, high-density electric source imaging (HD-ESI), SPECT and PET in epilepsy surgery candidates. Clinical Neurophysiology, 127(1), 150-155. doi:10.1016/j.clinph.2015.03.025

 

Li, W., Chen, Z., Yan, N., Jones, J. A., Guo, Z., Huang, X., . . . Liu, H. (2016). Temporal Lobe Epilepsy Alters Auditory-motor Integration For Voice Control. Sci Rep, 6, 28909. doi:10.1038/srep28909

 

Liao, K., Xiao, R., Gonzalez, J., & Ding, L. (2014). Decoding individual finger movements from one hand using human EEG signals. PLoS One, 9(1), e85192. doi:10.1371/journal.pone.0085192

 

Lippe, S., Roy, M.-S., Arcand, C., Scantlebury, M. H., Carmant, L., & Lassonde, M. (2009). Altered EEG spectral activity and attentional behavioral deficits following prolonged febrile seizures: a pilot study. Epileptic Disorders, 11(1), 10-19.

 

Malpass, K. (2011). Epilepsy: Electric source imaging—an inexpensive and reliable method to estimate the epileptic focus. Nature Reviews Neurology, 7(12), 658-658.

 

Megevand, P., Spinelli, L., Genetti, M., Brodbeck, V., Momjian, S., Schaller, K., . . . Seeck, M. (2014). Electric source imaging of interictal activity accurately localises the seizure onset zone. Journal of Neurology, Neurosurgery & Psychiatry, 85(1), 38-43. doi:10.1136/jnnp-2013-305515

 

Michel, C. M., Lantz, G., Spinelli, L., de Peralta Menendez, R., Landis, T., & Seeck, M. (2004). 128-channel EEG source imaging in epilepsy: clinical yield and localization precision. Journal of Clinical Neurophysiology, 21(2), 71-83.

 

Michel, C. M., Murray, M. M., Lantz, G., Gonzalez, S., Spinelli, L., & Grave de Peralta, R. (2004). EEG source imaging. Clinical Neurophysiology, 115(10), 2195-2222. doi:10.1016/j.clinph.2004.06.001

 

Miller, K. J., Schalk, G., Hermes, D., Ojemann, J. G., & Rao, R. P. (2016). Spontaneous Decoding of the Timing and Content of Human Object Perception from Cortical Surface Recordings Reveals Complementary Information in the Event-Related Potential and Broadband Spectral Change. PLoS Comput Biol, 12(1), e1004660. doi:10.1371/journal.pcbi.1004660

 

Mintz, M., LeGoff, D., Scornaienchi, J., Brown, M., Levin-Allen, S., Mintz, P., & Smith, C. (2009). The Underrecognized Epilepsy Spectrum: The Effects of Levetiracetam on Neuropsychological Functioning in Relation to Subclinical Spike Production. Journal of Child Neurology, 24(7), 807-815.

 

Niso, G., Carrasco, S., Gudín, M., Maestú, F., del-Pozo, F., & Pereda, E. (2015). What graph theory actually tells us about resting state interictal MEG epileptic activity. NeuroImage: Clinical, 8, 503-515. doi:10.1016/j.nicl.2015.05.008

 

Pittau, F., Grouiller, F., Spinelli, L., Seeck, M., Michel, C. M., & Vulliemoz, S. (2014). The role of functional neuroimaging in pre-surgical epilepsy evaluation. Front Neurol, 5, 31. doi:10.3389/fneur.2014.00031

 

Pittau, F., Megevand, P., Sheybani, L., Abela, E., Grouiller, F., Spinelli, L., . . . Vulliemoz, S. (2014). Mapping epileptic activity: sources or networks for the clinicians? Front Neurol, 5, 218. doi:10.3389/fneur.2014.00218

 

Podubnaia-Birca, A. (2008). Electro-clinical characteristics of febrile seizures and the risk of epilepsy. University of Montreal, 1-132.

 

Ramon, C., & Holmes, M. D. (2012). Noninvasive epileptic seizure localization from stochastic behavior of short duration interictal high density scalp EEG data. Brain Topogr, 25(1), 106-115. doi:10.1007/s10548-011-0188-8

 

Ramon, C., & Holmes, M. D. (2013). Noninvasive localization of epileptic sites from stable phase synchronization patterns on different days derived from short duration interictal scalp dEEG. Brain Topogr, 26(1), 1-8. doi:10.1007/s10548-012-0236-z

 

Ramon, C., Holmes, M. D., Freeman, W. J., Gratkowski, M., Eriksen, K. J., & Haueisen, J. (2009). Power spectral density changes and language lateralization during covert object naming tasks measured with high-density EEG recordings. Epilepsy & Behavior, 14(1), 54-59. doi:10.1016/j.yebeh.2008.08.018

 

Ramon, C., Holmes, M. D., Freeman, W. J., McElroy, R., & Rezvanian, E. (2008). Comparative analysis of temporal dynamics of EEG and phase synchronization of EEG to localize epileptic sites from high density scalp EEG interictal recordings. Engineering in Medicine and Biology Society, 4548-4550. doi:10.1109/IEMBS.2008.4650224  

 

Rosenow, F., Bast, T., Czech, T., Feucht, M., Hans, V. H., Helmstaedter, C., . . . Polster, T. (2016). Revised version of quality guidelines for presurgical epilepsy evaluation and surgical epilepsy therapy issued by the Austrian, German, and Swiss working group on presurgical epilepsy diagnosis and operative epilepsy treatment. Epilepsia, 57(8), 1215-1220.

 

Sheppard, E., Birca, A., Carmant, L., Lortie, A., Vannassing, P., Lassonde, M., & Lippe, S. (2013). Children with a history of atypical febrile seizures show abnormal steady state visual evoked potential brain responses. Epilepsy Behav, 27(1), 90-94. doi:10.1016/j.yebeh.2012.12.023

 

Sohrabpour, A., Lu, Y., Kankirawatana, P., Blount, J., Kim, H., & He, B. (2015). Effect of EEG electrode number on epileptic source localization in pediatric patients. Clin Neurophysiol. doi:10.1016/j.clinph.2014.05.038

 

Song, J., Davey, C., Poulsen, C., Luu, P., Turovets, S., Anderson, E., . . . Tucker, D. (2015). EEG source localization: Sensor density and head surface coverage. J Neurosci Methods, 256, 9-21. doi:10.1016/j.jneumeth.2015.08.015

 

Song, J., Tucker, D. M., Gilbert, T., Hou, J., Mattson, C., Luu, P., & Holmes, M. D. (2013). Methods for examining electrophysiological coherence in epileptic networks. Front Neurol, 4, 55. doi:10.3389/fneur.2013.00055

 

Sperli, F., Spinelli, L., Seeck, M., Kurian, M., Michel, C. M., & Lantz, G. (2006). EEG source imaging in pediatric epilepsy surgery: a new perspective in presurgical workup. Epilepsia, 47(6), 981-990.

 

Staljanssens, W., Strobbe, G., Van Holen, R., Birot, G., Gschwind, M., Seeck, M., . . . van Mierlo, P. (2016). Seizure onset zone localization from ictal high-density EEG in refractory focal epilepsy. Brain Topography, 1-15.

 

Storti, S., Formaggio, E., Franchini, E., Bongiovanni, L. G., Cerini, R., Fiaschi, A., . . . Manganotti, P. (2012). A multimodal imaging approach to the evaluation of post-traumatic epilepsy. Magn Reson Mater Phy, 1-6. doi:10.1007/s10334-012-0316-9

 

Storti, S. F., Boscolo Galazzo, I., Del Felice, A., Pizzini, F. B., Arcaro, C., Formaggio, E., . . . Manganotti, P. (2014). Combining ESI, ASL and PET for quantitative assessment of drug-resistant focal epilepsy. NeuroImage, 102, 49-59. doi:10.1016/j.neuroimage.2013.06.028

 

Tamburin, S., Turri, G., Kuhdari, P., Fiaschi, A., & Manganotti, P. (2012). Unilateral fixed mydriasis: an uncommon presentation of temporal lobe epilepsy. J Neurol, 259(2), 355-357. doi:10.1007/s00415-011-6159-x

 

Tsai, J. J., Norcia, A. M., Ales, J. M., & Wade, A. R. (2011). Contrast gain control abnormalities in idiopathic generalized epilepsy. American Neurological Assocation, 70(4), 574-582. doi:DOI: 10.1002/ana.22462

 

Tucker, D. M., Brown, M., Luu, P., & Holmes, M. D. (2007). Discharges in ventromedial frontal cortex during absence spells. Epilepsy & Behavior, 11(4), 546-557. doi:10.1016/j.yebeh.2007.04.023

 

Tucker, D. M., Waters, A. C., & Holmes, M. D. (2009). Transition from cortical slow oscillations of sleep to spike-wave seizures. Clinical Neurophysiology, 120(12), 2055-2062. doi:10.1016/j.clinph.2009.07.047

 

Vanhatalo, S., Voipio, J., Dewaraja, A., Holmes, M. D., & Miller, J. W. (2003). Topography and elimination of slow EEG responses related to tongue movements. NeuroImage, 20, 1419-1423. doi:10.1016/S1053-8119(03)00392-6

 

Varcin, K. J., Nelson, C. A., Ko, J., Sahin, M., Wu, J. Y., & Jeste, S. S. (2015). Visual Evoked Potentials as a Readout of Cortical Function in Infants With Tuberous Sclerosis Complex. Journal of Child Neurology, 0883073815587328. doi:10.1177/0883073815587328

 

Wang, S., Xiao, C., Tsai, J. J., Chaovalitwongse, W., & Grabowski, T. J. (2016). A Novel Mutual-Information-Guided Sparse Feature Selection Approach for Epilepsy Diagnosis Using Interictal EEG Signals. Paper presented at the International Conference on Brain and Health Informatics.

 

Wijnen, B. F., de Kinderen, R. J., Colon, A. J., Dirksen, C. D., Essers, B. A., Hiligsmann, M., . . . Evers, S. M. (2014). Eliciting patients' preferences for epilepsy diagnostics: a discrete choice experiment. Epilepsy Behav, 31, 102-109. doi:10.1016/j.yebeh.2013.11.029

Won, D., Kim, W., Chaovalitwongse, W. A., & Tsai, J. J. (2016). Altered visual contrast gain control is sensitive for idiopathic generalized epilepsies. Clinical Neurophysiology.

 

Yamazaki, M., Terrill, M., Fujimoto, A., Yamamoto, T., & Tucker, D. M. (2012). Integrating dense array EEG in the presurgical evaluation of temporal lobe epilepsy. ISRN Neurol, 2012, 924081. doi:10.5402/2012/924081

 

Yamazaki, M., Tucker, D. M., Fujimoto, A., Yamazoe, T., Okanishi, T., Yokota, T., . . . Yamamoto, T. (2012). Comparison of dense array EEG with simultaneous intracranial EEG for Interictal spike detection and localization. Epilepsy Research, 98(2-3), 166-173. doi:10.1016/j.eplepsyres.2011.09.007

 

Yamazaki, M., Tucker, D. M., Terrill, M., Fujimoto, A., & Yamamoto, T. (2013). Dense array EEG source estimation in neocortical epilepsy. Front Neurol, 4, 42. doi:10.3389/fneur.2013.00042


The applications referenced on this page are research or investigational only and are not intended to imply a specific indication for use of the EGI systems beyond their intended use statement on file with the FDA.